Opioids for dyspnoea

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منابع مشابه

Opioids for dyspnoea.

o understand, define, and treat dys-pnoea is difficult. It is an under-appreciated problem in respiratory medicine, cardiology, and palliative medicine, and it is often hard to know when to supplement the treatment of an underlying disease by pure palliation. In this issue of Thorax Jennings et al 1 present a meta-analysis of randomised controlled trials of opioids as treatment for dys-pnoea, w...

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Review: oral or parenteral opioids alleviate dyspnoea.

Data extraction Data were extracted by 2 independent reviewers on disease causing dyspnoea, intervention (opioid used and dosage), study methodology, and results. Study quality was assessed using the 5 point Jadad scale and the Cochrane Collaboration criteria for concealment. Main outcome measure was a subjective assessment of dyspnoea. In studies of patients at rest, the breathlessness measure...

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Palliation of dyspnoea in advanced COPD: revisiting a role for opioids.

Chronic obstructive pulmonary disease (COPD) will be the third leading cause of death worldwide by 2020. The burdens of this increasingly prevalent illness borne by patients, their family caregivers and the healthcare system are substantial. Dyspnoea as the predominant symptom becomes increasingly difficult to palliate as COPD progresses through advanced stages and, for 50% of patients, can bec...

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A systematic review of the use of opioids in the management of dyspnoea.

BACKGROUND Opioids are commonly used to treat dyspnoea in palliative medicine but there has been no formal evaluation of the evidence for their effectiveness in the treatment of dyspnoea. A systematic review was therefore carried out to examine this. METHODS The criteria for inclusion required that studies were double blind, randomised, placebo controlled trials of opioids for the treatment o...

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Endogenous opioids modify dyspnoea during treadmill exercise in patients with COPD.

Exogenous opioid drugs, such as morphine, relieve breathlessness. The present study hypothesis was that endogenous opioids, released during the stress of exercise, modify dyspnoea in patients with chronic obstructive pulmonary disease. After familiarisation, patients performed an incremental treadmill exercise test followed by constant work on the treadmill for 10 min. At subsequent visits (2 t...

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ژورنال

عنوان ژورنال: Thorax

سال: 2002

ISSN: 0040-6376

DOI: 10.1136/thorax.57.11.922